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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INPP5D
All Species:
8.18
Human Site:
S978
Identified Species:
18
UniProt:
Q92835
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92835
NP_001017915.1
1189
133292
S978
S
P
K
K
F
L
P
S
T
A
N
R
G
L
P
Chimpanzee
Pan troglodytes
XP_526066
929
104074
D735
T
Q
E
S
R
P
S
D
L
G
K
N
A
G
D
Rhesus Macaque
Macaca mulatta
XP_001114794
1258
138636
A1012
A
R
A
P
V
P
P
A
T
K
N
K
V
A
I
Dog
Lupus familis
XP_542327
1264
138869
A1018
A
R
A
P
V
P
P
A
T
K
N
K
V
A
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9ES52
1191
133524
S979
S
P
K
K
F
S
S
S
T
A
N
R
G
P
C
Rat
Rattus norvegicus
P97573
1190
133575
S978
S
P
K
K
F
S
S
S
T
A
N
R
G
S
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520934
1019
113512
K825
P
G
K
T
D
R
K
K
N
S
F
L
P
P
A
Chicken
Gallus gallus
XP_422567
1182
133482
N980
P
V
S
R
S
I
C
N
R
S
Q
D
H
L
P
Frog
Xenopus laevis
Q6P4S2
1019
115278
Q825
L
R
K
E
D
T
E
Q
Q
F
P
F
C
T
I
Zebra Danio
Brachydanio rerio
Q2I6J1
1266
140353
S1017
A
Q
G
R
W
Q
T
S
G
R
S
V
R
P
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789838
1327
148052
G1050
S
A
D
P
M
D
G
G
E
Y
M
G
L
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.8
41.3
40.9
N.A.
87.8
87.8
N.A.
38.7
68.2
56.5
43.1
N.A.
N.A.
N.A.
N.A.
31
Protein Similarity:
100
77.8
57.5
56.8
N.A.
92.1
92
N.A.
48.5
78.7
67.1
57.9
N.A.
N.A.
N.A.
N.A.
47.3
P-Site Identity:
100
0
20
20
N.A.
73.3
73.3
N.A.
6.6
13.3
6.6
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
13.3
40
40
N.A.
73.3
73.3
N.A.
13.3
40
13.3
33.3
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
28
10
19
0
0
0
0
19
0
28
0
0
10
19
10
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
19
% C
% Asp:
0
0
10
0
19
10
0
10
0
0
0
10
0
0
10
% D
% Glu:
0
0
10
10
0
0
10
0
10
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
28
0
0
0
0
10
10
10
0
0
0
% F
% Gly:
0
10
10
0
0
0
10
10
10
10
0
10
28
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
37
% I
% Lys:
0
0
46
28
0
0
10
10
0
19
10
19
0
0
0
% K
% Leu:
10
0
0
0
0
10
0
0
10
0
0
10
10
19
10
% L
% Met:
0
0
0
0
10
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
10
0
46
10
0
0
0
% N
% Pro:
19
28
0
28
0
28
28
0
0
0
10
0
10
28
19
% P
% Gln:
0
19
0
0
0
10
0
10
10
0
10
0
0
0
0
% Q
% Arg:
0
28
0
19
10
10
0
0
10
10
0
28
10
0
0
% R
% Ser:
37
0
10
10
10
19
28
37
0
19
10
0
0
19
0
% S
% Thr:
10
0
0
10
0
10
10
0
46
0
0
0
0
10
0
% T
% Val:
0
10
0
0
19
0
0
0
0
0
0
10
19
0
0
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _